Link Between Statins and Diabetes

Long-term use of statins has been linked to the development of diabetes mellitus (DM) which increases CVD risk. Areas covered: We discussed the reported incidence of DM in statin users, various possible mechanisms responsible for the development of DM and the clinical implications of this association on CVD risk. Relevant supporting literature was identified using MEDLINE/EMBASE search. Expert opinion: Data from available RCTs and observational studies suggest a 10-45% higher risk of new-onset DM with statin use compared to nonusers. Several cellular, molecular, and genetic mechanisms, and lifestyle changes have been studied and discussed as potential underlying mechanisms responsible for this elevated DM risk with statin therapy. The mode of the diabetogenic action of statins is still unclear and an interplay of pancreatic and peripheral effects in the pathogenesis of DM is a possibility.

– Statins and the potential for higher diabetes mellitus risk

On July 30, 2015 I posted an embedded video from MSNBC (MSNBC reports: Link Between Statins and Diabetes – http://www.msnbc.msn.com/id/32545640). The article & video have since been deleted from their website. One must ask: WHY?

Diabetes rates are soaring – How can we stop it?

June 30, 2011

Diabetes rates are soaring – How can we stop it?

This topic is near and dear to my heart. I am re-posting this blogpost, which was posted on June 29, 2011 by the Instituted for Integrative Nutrition (my nutrition school), in hopes that this information will be distributed to many of our loved ones who have diabetes. Please forward this blogpost to your friends and followers. Thank you.

More than 350 million people worldwide now have diabetes. That’s greater than the entire population of the United States (307 million), and more than double the number of diabetes cases in 1980. These frightening statistics fromThe Guardian will only get worse if we do not make dramatic changes to the our accustomed lifestyles.

By 2020, the UnitedHealth Group anticipates that 50% of Americans could have diabetes or prediabetes.

As much as 95% of these cases are predicted to be Type 2 adult-onset diabetes, a condition highly correlated to obesity, poor diet, and lack of physical activity. In some cases, the condition can lead to kidney failure, heart attack, or stroke.

To reverse this trend, we’ve got to start at the source: the Standard American Diet and lifestyle that is now proliferating through all the nations of the world

people on bikes

Non-smoking adults at a normal weight who eat a healthy diet and get regular exercise have been proven to be 89% less likely to develop diabetes. That’s a very encouraging prevention statistic!

What about those already diagnosed with diabetes? Just earlier this month, researchers had a breakthrough in diabetes care. As reported by the BBC, eleven people who had been diagnosed with Type 2 diabetes underwent a drastic eight-week diet regimen of 600 calories a day. At the end of the study, 7 of the 11 participants no longer had diabetes.

The researchers anticipate that by combining a healthy diet with regular exercise, these former diabetics may be able to live diabetes-free the rest of their lives. This is great news for those 350 million already coping with diabetes.

In a 2009 documentary, Simply Raw, six diabetics switched to a raw food diet for 30 days and found their “incurable” disease wasn’t so permanent after all.

The prevention and the cure are based on the same principle – live healthfully. We can start reducing the number of people affected by diabetes as soon as we can embrace the lifestyle we all know we should: eat right and exercise.

What advice do you have for someone battling diabetes?

Why it’s important to question your doctor

January 25, 2011

Why it’s important to question your doctor

Over the past several years, my husband has been under the care of an endocrinologist for the treatment of diabetes. My husband’s overall cholesterol level is good, but his LDL/HDL ratio is not, so at almost every visit, the Dr. has tried to sway him to utilize a statin medication.

What is a statin?
Statins are usually used to lower cholesterol.They work by blocking the body’s ability to produce cholesterol and by helping your body reabsorb plaque that has built up on the artery walls, hopefully preventing additional blockage in the artery and thus preventing heart attacks. However, the use of statins does not come without side effects, which may include depression, muscle pain and weakness, neuropathy, heart failure, dizziness, cognitive impairment, cancer, pancreatitis and liver damage). According to the National Health Alliance, “a recent study shows that the statin drug simvastatin, which the government is advocating we take to lower cholesterol levels, actually weakens our immune system and makes it difficult to fight off bacterial infections.” and that high cholesterol actually protects us against infection!

Now, getting back to my story:

At our first visit, we questioned the Dr. at length about the source of the clinical studies on which he based his recommendation, we felt that the potential risks involved by far outweighed the KNOWN benefits of the drug for a man his age. At almost every visit, my husband listened to the recommendation for a statin drug, but walked away without taking the Rx. A few months ago, my husband was seen by a Nurse Practitioner (NP) instead of by the Doctor. The NP was very patient in answering all of our questions. We asked her about the use of Red Yeast Rice or Niacin in lieu of a statin. She said that she has seen positive results from both and suggested that he try the Red Yeast Rice first and if that did not help, that he try the Niacin.

Last month, the Dr. was still recommending the use of a statin medication. We asked him if it would not be wise for my husband to try Niacin instead, as we had previously discussed with the NP, and he looked at the latest lab results before answering. I must say that I was quite surprised at his response:

He said that he usually prescribes statins to his diabetic patients because it is believed that the statins reduce the risk of coronary disease. However, in my husband’s case, the statins wouldn’t work. In fact, Niacin would be a better option.

He further explained that the reason he recommends niacin instead of a statin is because, in his case the bad cholesterol is fine but the good cholesterol is low. So why did he not recommend niacin earlier?

What if we had never asked?

By the way, when someone begins to take a statin, he/she will probably take the medication for LIFE. Imagine the economic implications associated with this – for both the patient and the pharmaceutical companies. More about this later…

Sources:

http://www.mayoclinic.com/health/statins/CL00010
http://www.westonaprice.org/modern-diseases/cardiovascular-disease/581-dangers-of-statin-drugs.html
http://www.anh-usa.org/statin-drugs-open-us-up-to-foodborne-illnesses/

*Note – My husband has graciously given me permission to write about him on this very important topic.